I've been working on a web based game for the DSI (and 3DS) that could be the first of it's kind.
I only started developing last weekend and I'm aiming to get an Alpha release out sometime next week.
I'm not going to say much at the moment, but it's an RTS style and will be very interactive with other players.
When the Alpha goes out the game will be publicly open for anyone who wants to check out the pre release version.
Check back soon to keep updated on this!
PS: This has nothing to do with DSE, different hosting, code, accounts, everything.